Parotid Secretion and Feeding in Sheep Following lntraventricular Injections of l-Norepinephrine, dl-Isoproterenol, Pentobarbital, and Carbachol
Year: 1974
Type: article
Abstract: Our cbjective was to test the role of sensory cues in chemically stimulated feeding.We measured whether salivation rate changed only secondarily to the elicited feeding or if it changed even in the absence of feed.Six wethers each were prepared with bilateral lateral ventricular guides and a parotid duct cannula.Following wethers' recovery from surgery, feed intakes and parotid flows were measured after lateral ventricular injections of 1-norepinephrine (540 nmol), dl-isoproterenol (20 nmol), pentobarbital (100 pmol), carbachol (55 nmol), and synthetic cerebrospinal fluid.These tests were compared to similar tests in which feed was withheld for 1 h following injection.With 1-norepinephrine (plus feed) salivary flow was greatest followed by pentobarbital.Carbachol elicited significant feeding, but salivation was suppressed.When feed was withheld as compared to when feed was present, parotid flow decreased in all tests.Subcutaneous injeetion of carbaehol was followed by salivation which was noxxnal following 55 nmol and copious after 2,700 nmol.We conclude because salivation increased only when feeding was permitted that the feeding was not the result of chemically stimulated sensory cues whieh elicit feeding antieipatory salivation.
Source: Journal of Dairy Science
Authors: C.A. Baile, F.H. Martin
Institution: University of Pennsylvania
Language: English
Subfield: Endocrine and Autonomic Systems
Field: Neuroscience
Domain: Life Sciences
Open Access status: bronze
Funder: National Science Foundation
OpenAlex ID: W1969914067