Year: 2012
Type: article
Abstract: This paper reviews the newest developments in computational cardiology. It focuses on the contribution of cardiac modeling to the development of new therapies as well as the advancement of existing ones for cardiac arrhythmias and pump dysfunction. Reviewed are cardiac modeling efforts aimed at advancing and optimizing existent therapies for cardiac disease (defibrillation, ablation of ventricular tachycardia, and cardiac resynchronization therapy) and at suggesting novel treatments, including novel molecular targets, as well as efforts to use cardiac models in stratification of patients likely to benefit from a given therapy, and the use of models in diagnostic procedures.
Source: ISRN Cardiology
DOI: 10.5402/2012/269680
Author: Natalia A. Trayanova
Institution: Johns Hopkins University
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
Awards: G2009083703, Resynchronizing the Failing Heart: Insights from a Multiscale Cardiac Model, G3548004340, CDI Type-II: Collaborative Research: From Ion Channels to Blood Flow and Heart Sounds: A New Paradigm in Cyber-Enabled Multiphysical Analysis of Heart Function, Improved Targeting and Assessment of Electrophysiology Intervention, G5520316217, G5714341639, G5810046786, Redox Modification of the Arrhythmic Substrate in Heart Failure, G6996578372, Mechanically-Induced Spontaneous Arrhythmias in Acute Regional Ischemia
OpenAlex ID: W1970399645