Work

PEG-based gels for the release of proteins and the encapsulation of cells

Year: 1993

Type: article

Abstract: A PEG-based polymer matrix is developed within which biol. macromols. and living mammalian cells could be easily dispersed. Constraints placed upon such a matrix by a desire that it be generally processable in the presence of biol. macromols. and living cells include limiting temps. to physiol. or lower, working in oxygenated environments, avoiding exposure to cytotoxic monomers, avoiding exposure to org. solvents, and avoiding chem. reactions that readily modify functional groups found in proteins, such as carboxyls and amines. [on SciFinder (R)]

Source: Infoscience (Ecole Polytechnique Fédérale de Lausanne)

Authors: Jeffrey A. Hubbell, J. L. Hill-West, C. P. Pathak, Amarpreet S. Sawhney

Institution: The University of Texas at Austin

Language: English

Topic: Hydrogels: synthesis, properties, applications

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W197052676

FWCI:

Cites:

Cited by: 2

Related to: 10