Work

The Role of Deoxyribonucleic Acid in Ribonucleic Acid Synthesis, Iii. the Inhibition of the Enzymatic Synthesis of Ribonucleic Acid and Deoxyribonucleic Acid by Actinomycin D and Proflavin

Year: 1962

Type: article

Abstract: With advancements in stem cell technology, in vitro models using iPSC (induced pluripotent stem cells)-derived cardiomyocytes (iPSC-CM) and engineered heart tissues (EHT) can serve as powerful tools for disease modeling and drug screening. ...Fluorescent reporters of cardiac electrophysiology provide valuable information on heart cell and tissue function. However, motion artifacts caused by cardiac muscle contraction interfere with accurate measurement of fluorescence signals. Although drugs ...

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.48.7.1222

Authors: Jerard Hurwitz, J. J. Furth, M. Malamy, M. Alexander

Institution: New York University

Language: English

Topic: RNA and protein synthesis mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1970604670

FWCI: 33.22

Cites: 20

Cited by: 449

Related to: 10