Work

Recent Developments in the Biosynthesis of the Tropane Alkaloids1

Year: 1990

Type: article

Abstract: Recent work on the biosynthesis of the tropane moiety of cocaine, hyoscamine, scopolamine, and related alkaloids is reviewed. Revision of the generally accepted biosynthetic pathway to these alkaloids is now proposed in the light of new discoveries. New information on the biosynthesis of some of the acid moieties (benzoic, tiglic and tropic acid) of the tropane ester alkaloids is also discussed.

Source: Planta Medica

DOI: 10.1055/s-2006-960979

Author: Edward Leete

Institution: University of Minnesota

Language: English

Topic: Plant biochemistry and biosynthesis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Science Foundation, National Institutes of Health, National Institute of General Medical Sciences, Division of Chemistry

Awards: G6284259037, BIOSYNTHESIS OF COCAINE AND RELATED TROPANE ALKALOIDS, Enzymes Catalyzing the Biosynthesis of Alkaloids (Chemistry)