Work

Head circumference of children with Down syndrome (0–36 months)

Year: 1992

Type: article

Abstract: This study provides statistically appropriate head circumference reference curves for males and females with Down syndrome (DS) from birth to 36 months of age. A total of 239 males and 182 females from five study populations, yielding a combination of cross-sectional and longitudinal data, were used for the analysis. The method of least squares was used to test the fit of the growth model y = a+bx+c[log(x + 1)], where x is age in months. These standardized curves should provide information of value in the medical, physical, and developmental management of children with DS.

Source: American Journal of Medical Genetics

DOI: 10.1002/ajmg.1320420114