Work

The cellular effects of estrogens on neuroendocrine tissues

Year: 1988

Type: review

Abstract: Estrogen action on sensitive neurons in the rat diencephalon has been studied by morphologic techniques; evidence of estrogen action at every level is presented, including tracts, cells, circuitry and subcellular organelles. The demonstration in the arcuate nucleus of estrogen-induced synaptic remodelling, estrogen-induced postsynaptic membrane phenotypes, changes in intracellular membranes and rapid estrogen actions on neuronal endo-exocytosis indicates that cellular estrogen actions may underlie the neuronal control of reproduction.

Source: Journal of Steroid Biochemistry

DOI: 10.1016/0022-4731(88)90093-3

Authors: F. Naftolin, N.J. Maclusky, C.Z. Leranth, H.S. Sakamoto, L.M. Garcia-Segura

Institutions: Yale University, Instituto Cajal

Language: English

Topic: Estrogen and related hormone effects

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Eunice Kennedy Shriver National Institute of Child Health and Human Development