363: Early Detection of Severe Acute Graft-Versus-Host Disease using Plasma Markers of T-cell Activation
Year: 2008
Type: article
Abstract: Severe acute graft-versus-host disease (GVHD) is a significant cause of transplant related mortality in patients that receive allogeneic hematopoietic stem cell transplantation (HSCT). Treatment of grade III and IV GVHD is frequently ineffective. Preemptive treatment based on the early detection of cytokines associated with T-cell activation and subclinical GVHD might be a more effective strategy, similar to the monitoring of CMV infection after HSCT.
Institutions: Emory University, Winship Cancer Institute
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W1972633235