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Genetic Interaction between Distinct Dobrava Hantavirus Subtypes in Apodemus agrarius and A. flavicollis in Nature

Year: 2002
Type: article
Abstract: Dobrava virus (DOBV) occurs in two different rodent species, Apodemus flavicollis (DOBV-Af) and A. agrarius (DOBV-Aa). We sequenced the S and M genomic segments from sympatric DOBV-Af and DOBV-Aa strains which fell into two distinct genetic lineages. Molecular phylogenetic analyses gave evidence for genetic reassortment between S and M segments of DOBV-Af and DOBV-Aa and indicated homologous recombination events in DOBV evolution. DOBV-Af and DOBV-Aa are distinct but also subject to genetic exchanges that affect their evolutionary trajectories.
DOI: 10.1128/jvi.77.1.804-809.2003
Authors: Boris Klempa, Heiko A. Schmidt, Rainer Ulrich, Stefan Kaluz, Milan Labuda, Helga Meisel, Brian Hjelle, Detlev H. Krüger
Institutions: Humboldt-Universität zu Berlin, Charité – Universitätsmedizin Berlin, Max Planck Institute for Molecular Genetics, Slovak Academy of Sciences, Institute of Zoology of the Slovak Academy of Sciences, University of New Mexico
Language: English
Field: Medicine
Open Access status: green
OpenAlex ID: W1972944084
FWCI: 4.672
Cites: 27
Cited by: 83
Related to: 10