Work

Severe Congenital Malaria Acquired in utero

Year: 2010

Type: article

Study design: Case Report

Abstract: Vertical transmission of Plasmodium falciparum is under-recognized and usually associated with asymptomatic low-level parasitemia at birth. We report symptomatic congenital malaria presenting as a neonatal sepsis syndrome. The presence at birth of a high asexual parasitemia, gametocytemia, and splenomegaly indicated in utero rather than intrapartum transmission. The neonate was successfully treated with intravenous artesunate followed by oral dihydroartemisinin-piperaquine, without apparent adverse effects.

Source: American Journal of Tropical Medicine and Hygiene

DOI: 10.4269/ajtmh.2010.09-0744

Authors: Jeanne R. Poespoprodjo, Afdal Hasanuddin, Wendelina Fobia, Paulus Sugiarto, Enny Kenangalem, Daniel A. Lampah, Emiliana Tjitra, Ric N. Price, Nicholas M. Anstey

Institutions: Charles Darwin University, Menzies School of Health Research, National Institutes of Health, Badan Penelitian dan Pengembangan Kesehatan, Kementerian Kesehatan Republik Indonesia

Language: English

Topic: Malaria Research and Control

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Wellcome Trust, Menzies School of Health Research, Medical Research Council, National Health and Medical Research Council

Award: Optimising antimalarial combination therapies in an area coendemic for vivax and falciparum malaria

OpenAlex ID: W1973489086

FWCI: 5.069

Cites: 19

Cited by: 36

Related to: 10