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The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization

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Year: 2011
Type: article
Source: Nature Immunology
DOI: 10.1038/ni.2095
Authors: Sirish K Ippagunta, R K Subbarao Malireddi, Patrick J Shaw, Geoffrey A Neale, Lieselotte Vande Walle, Douglas R Green, Yoshinori Fukui, Mohamed Lamkanfi, Thirumala-Devi Kanneganti
Institutions: St. Jude Children's Research Hospital, Ghent University, Kyushu University, Medical Institute of Bioregulation, Kyushu University
Language: English

Topic: Inflammasome and immune disorders
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Japan Society for the Promotion of Science, National Institute of Allergy and Infectious Diseases, National Institute of Arthritis and Musculoskeletal and Skin Diseases
Awards: Role of IL-1alpha signaling in inflammatory diseases and host defense, NLR signaling in intestinal inflammation, Signaling and functions of CDM family proteins that acts as Rac GEFs
OpenAlex ID: W1973645470
FWCI: 5.64
Cites: 54
Cited by: 114
Related to: 10
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