Year: 2007
Type: article
Abstract: Mitochondrial research has influenced concepts in anthropology, human physiology and pathophysiology. We present here direct evidence that human recombinant viruses can localize in mitochondria to disrupt their integrity. This finding, while opening new perspectives in viral gene therapy, may provide new insights into the pathogenesis, prevention and treatment of viral diseases. In addition, it may advance the current understanding of cell evolution.
Source: NeuroImmunoModulation
DOI: 10.1159/000113065
Authors: Salvatore Alesci, Mones Abu-Asab, Shiromi M. Perera, Maria Tsokos, John C. Morris, Karel Pacak
Institutions: National Institute of Mental Health, National Institute of Mental Health, National Institute of Mental Health, National Institutes of Health, National Cancer Institute, Center for Cancer Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Wyeth, National Cancer Institute, National Cancer Institute
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: bronze
Award: G6374948078
OpenAlex ID: W1974333864