Work

A Flood of Microbial Genomes–Do We Need More?

Year: 2009
Type: article
Abstract: Complete genome sequences of important bacterial pathogens and industrial organisms hold significant consequences and opportunities for human health, industry and the environment.Addressing biological and clinical problems through genome sequence based approaches offers many commercial opportunities.The aftermath of whole genome sequencing has revealed new insights into evolution of bacterial lifestyles including strategies for adaptation to new niches and overcoming competitors.Whole genome sequences representing more than 1500 prokaryotic organisms combined with the dozens (to hundreds) of strain re-sequencing projects are posing mind boggling problems on the optimal utilization of the resultant 'omic' datasets.Consequently, microbiologists are confronted with the challenge to translate these data into better human and animal healthcare solutions and pursue basic research approaches to interpret the data in ecological and evolutionary perspectives.New informatic approaches towards optimal utilization, holistic integration and meaningful interpretation of the genome sequence data are extremely necessary.
Source: PLoS ONE
Author: Niyaz Ahmed
Language: English
Open Access status: gold
Estimated APC paid: $2,382
OpenAlex ID: W1974588099
FWCI: 2.816
Cites: 29
Cited by: 36
Related to: 10