Year: 2000
Type: article
Abstract: Oral tolerance, the specific suppression of cellular and/or humoral immune responses to an antigen by prior administration of the antigen by the oral route, probably evolved to prevent hypersensitivity reactions to food proteins and bacterial antigens present in the mucosal flora. As with other forms of immunologic tolerance, oral tolerance also provides mechanisms to suppress pathologic reactivity against self and, thus, to prevent or treat autoimmune diseases.
DOI: 10.1172/jci11348
Author: Howard L. Weiner
Institutions: Brigham and Women's Hospital, Harvard University
Language: English
Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W1974798515