A nondenaturing zwitterionic detergent for membrane biochemistry: design and synthesis.
Year: 1980
Type: article
Abstract: The synthesis and evaluation of a new detergent that is a zwitterionic derivative of cholic acid is presented. This detergent combines the useful properties of both the sulfobetaine-type detergents and the bile salt anions. The new detergent proved to be effective at solubilizing membrane proteins in a nondenatured state.
Author: L M Hjelmeland
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W1975224651