Work

Localization of the Human Gene for Macrophage Migration Inhibitory Factor (MIF) to Chromosome 22q11.2

Year: 1997

Type: article

Abstract: Macrophage migration inhibitory factor (MIF) is a lymphokine activity associated with early phases of the inflammatory response. The name MIF was later given to a small protein identified by expression cloning from activated T-cells. This protein is widely expressed in tissues regardless of immune status and has been identified with several different activities. Most recently it has become clear that MIF belongs to a superfamily of small isomerases. Whatever its physiological role(s), MIF gene expression is induced by different growth factors in a delayed early responses and is associated with processes of proliferation and differentiation. 16 refs., 1 fig.

Source: Genomics

DOI: 10.1006/geno.1996.4505

Authors: Marcia Budarf, Terrence McDonald, Beatrice Sellinger, Christine Kozak, Caroline Graham, Graeme Wistow

Institutions: Children's Hospital of Philadelphia, University of Pennsylvania, National Institutes of Health, National Eye Institute

Language: English

Topic: Macrophage Migration Inhibitory Factor

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,980