Work

Spiroguanidine rhodamines as fluorogenic probes for lysophosphatidic acid

Year: 2014

Type: article

Abstract: Direct determination of total lysophosphatidic acid (LPA) was accomplished using newly developed spiroguanidines derived from rhodamine B as universal fluorogenic probes. Optimum conditions for the quantitative analysis of total LPA were investigated. The linear range for the determination of total LPA is up to 5 μM with a limit of detection of 0.512 μM.

Source: Chemical Communications

DOI: 10.1039/c4cc08818b

Authors: Lei Wang, Martha Sibrian-Vazquez, Jorge O. Escobedo, Jialu Wang, Richard G. Moore, Robert M. Strongin

Institutions: Portland State University, Brown University

Language: English

Topic: Molecular Sensors and Ion Detection

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute

Award: Development of an Assay for the Early Detection of Ovarian Cancer