Calibration of myocardial iron concentration against T2-star Cardiovascular Magnetic Resonance
Year: 2009
Type: article
Abstract: Heart failure secondary to myocardial siderosis remains a major problem for patients with transfusional iron overload. Direct measurement of myocardial iron concentration by biopsy is not only highly invasive but unreliable due to uneven myocardial iron deposition. T2*cardiovascular magnetic resonance (CMR) is the only non-invasive technique which is able to assess tissue iron levels. This is a rapid, robust technique with proven reproducibility and inter-site transferability which has been accepted as part of clinical practice worldwide [ 1 ]. However, little data is available on the calibration of T2* values against tissue concentration of iron [ 2 ].
Authors: John-Paul Carpenter, Taigang He, Paul Kirk, Lisa J Anderson, John B Porter, John Wood, Renzo Galanello, Gianluca Forni, Gualtiero Catani, Suthat Fucharoen, Adam Fleming, Mike House, Greg Black, David N Firmin, Timothy G St Pierre, Dudley J Pennell
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,000
OpenAlex ID: W1976142822