Year: 2002
Type: article
Abstract: We report a case of RCZ caused by Rhizopus arrhizus (oryzae in an 84-year-old woman with poorly controlled diabetes.She presented with a right-sided facial droop of short origin, being generally unwell and 'off legs' over 2 weeks with reduced appetite.Initial non-conclusive CT scans and late in disease appearance of key markers of RCZ were probably factors permitting mycosis to rapidly progress in its course.Despite an intensive antifungal therapy with AmBisome and Insulin sliding scale, patient rapidly succumbed within 4 days of presenting.Fine needle aspiration cytology has been suggested as a possible, less invasive, easier and equally effective alternative to pre op biopsy.The key to successful reduction in morbidity and mortality associated with this rapidly fatal disease is increasing awareness of the disease, an early diagnosis, correction of underlying metabolic derangement, prompt intensive antifungal therapy with amphotericin B and radical surgical debridement of the necrotic tissue.Successful treatment of fungal meningitis and arachnoiditis with IV voriconazole in chronic gramdomatous disease (CGD)
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,900
OpenAlex ID: W1976694586