Work

The relationship between oxidative stress and nonalcoholic fatty liver disease: Its effects on the development of nonalcoholic steatohepatitis

Year: 2013

Type: review

Abstract: Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are the most common underlying causes of chronic liver injury. They are associated with a wide spectrum of hepatic disorders including basic steatosis, steatohepatitis, and cirrhosis. The molecular and cellular mechanisms underlying hepatic injury in NAFLD and NASH are still unknown. This review describes the roles of oxidative stress and inflammatory responses in the pathogenesis of NAFLD and its progression to NASH.

Source: Redox Report

DOI: 10.1179/1351000213y.0000000050

Authors: Fatma Ucar, Sevilay Sezer, Serpil Erdogan, Sumeyya Akyol, Ferah Armutcu, Omer Akyol

Institutions: Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Ankara Numune Eğitim ve Araştırma Hastanesi, Tokat Gaziosmanpaşa Üniversitesi, Turgut Özal University, Fatih University, Hacettepe University

Language: English

Topic: Liver Disease Diagnosis and Treatment

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W1976902613

FWCI: 0.709

Cites: 59

Cited by: 146

Related to: 10