Work

Fluconazole resistant non-albicans vaginal yeast in HIV seronegative women with vaginal discharge in Pune, India

Year: 2004

Type: article

Abstract: Vaginal candidiasis due to azole-resistant non-C. albicans strains is increasingly seen in women with vaginitis.1 This study was conducted to assess the fluconazole susceptibility and potential host factors associated with vaginal Candida species from women with vaginal discharge. Vaginal swabs were obtained from 133 of 186 women who presented with discharge due to reproductive tract infections at an STI clinic in a tertiary care government hospital from April 2001 to August 2002. The swabs were processed by standard mycological techniques.2,3 Candida isolates obtained were speciated and evaluated for in vitro fluconazole susceptibility by broth microdilution according to standard recommended guidelines.2,4 Infections were diagnosed by recommended methods5 and HIV testing conducted for all women based on guidelines issued by the National AIDS Control Organisation, India. All procedures and tests were conducted following written informed consent. Sociodemographic variables and patient history were recorded in a questionnaire. Data were analysed using the χ2 test (Table 1).

Source: International Journal of Infectious Diseases

DOI: 10.1016/j.ijid.2003.11.007