Work

The Role of Neuroplasticity and Cognitive Reserve in Aging With HIV

Year: 2013

Type: article

Abstract: By and large, the immune systems of people infected with HIV are being protected and maintained by advances in highly active antiretroviral therapy; as such, this is extending the lives of people into old age. Unfortunately, for many living with this disease, HIV is associated with neuroinflammation, co-morbidities, and accelerated aging which can compromise brain function, resulting in cognitive deficits. The purpose of this article is to highlight how to interpret these deficits within the framework of neuroplasticity and cognitive reserve for this clinical population. We suggest several recommendations for cognitive rehabilitation and mitigation such as addressing lifestyle factors, psychostimulants, cognitive remediation therapy, and treatment of depression and anxiety. Implications for nursing research and practice are posited.

Source: Journal of Neuroscience Nursing

DOI: 10.1097/jnn.0b013e31829d8b29

Authors: David E. Vance, Pariya L. Fazeli, Joan S. Grant, Larry Z. Slater, James L. Raper

Institutions: University of Alabama at Birmingham, University of California San Diego, UAB Medicine, New York University, University of Alabama

Language: English

Topic: HIV Research and Treatment

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Mental Health