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Determination by Raman Spectroscopy of the pKa of N5 of Dihydrofolate Bound to Dihydrofolate Reductase: Mechanistic Implications

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Year: 1994
Type: article
Source: Biochemistry
DOI: 10.1021/bi00189a001
Authors: Y.-Q. Chen, Joseph Kraut, Raymond L. Blakley, Robert Callender
Institutions: City College of New York, City University of New York, University of California San Diego, St. Jude Children's Research Hospital
Language: English

Topic: Chemical Reaction Mechanisms
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences
Awards: G2034720357, G2359706094, G3214237860, VIBRATIONAL AND DYNAMICAL STUDIES OF ENZYMES, STRUCTURAL STUDIES ON DIHYDROFOLATE REDUCTASE, CRYSTALLOGRAPHIC STUDIES OF DIHYDROFOLATE REDUCTASE
OpenAlex ID: W1978342265
FWCI: 2.464
Cites: 26
Cited by: 76
Related to: 10
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