Work

Effects of muscle fiber motion on diffuse correlation spectroscopy blood flow measurements during exercise

Year: 2010

Type: article

Abstract: The influence of muscle fiber motion during exercise on diffuse correlation spectroscopy (DCS) measurements of skeletal muscle blood flow is explored. Isotonic (with muscle fiber motion) and isometric (without muscle fiber motion) plantar flexion exercises were performed at 30% of maximal force on a dynamometer, and muscle blood flow was continuously monitored on the medial gastrocnemius (calf) muscle of a healthy volunteer using DCS. During exercise, dynamometer recordings including footplate position, footplate angular velocity, and plantar flexion torque were obtained. Muscle fiber motions introduced artifacts into the DCS signals, causing an overestimation of blood flow changes. We show how proper co-registration of dynamometer recordings and DCS measurements enables separation of the true blood flow responses during exercise from those affected by the motion artifacts.

Source: Biomedical Optics Express

DOI: 10.1364/boe.1.000500

Authors: Yu Shang, T. B. Symons, Turgut Durduran, A. G. Yodh, Guoqiang Yu

Institutions: University of Kentucky, Institute of Photonic Sciences, University of Pennsylvania

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: American Heart Association, National Institutes of Health, National Heart, Lung, and Blood Institute, National Center for Research Resources