Work

Gender and the Injured Brain

Year: 2008

Type: review

Abstract: Anesthesiologists are frequently confronted with patients who are at risk for neurological complications due to perioperative stroke or prior traumatic brain injury. In this review, we address the growing and fascinating body of data that suggests gender and sex steroids influence the pathophysiology of injury and outcome for these patients. Cerebral ischemia, traumatic brain injury, and epilepsy are reviewed in the context of potential sex differences in mechanisms and outcomes of brain injury and the role of estrogen, progesterone, and androgens in shaping these processes. Lastly, implications for current and future perioperative and intensive care are identified.

Source: Anesthesia & Analgesia

DOI: 10.1213/ane.0b013e31817326a5

Authors: Kamila Vagnerova, Ines P. Koerner, Patricia D. Hurn

Institution: Oregon Health & Science University

Language: English

Topic: Traumatic Brain Injury and Neurovascular Disturbances

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute of Nursing Research, National Institute of Neurological Disorders and Stroke