Work

Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry

Year: 2011

Type: article

Source: The EMBO Journal

DOI: 10.1038/emboj.2011.224

Authors: Pelagia Deriziotis, Ralph André, David M Smith, Rob Goold, Kerri J Kinghorn, Mark Kristiansen, James A Nathan, Rina Rosenzweig, Dasha Krutauz, Michael H Glickman, John Collinge, Alfred L Goldberg, Sarah J Tabrizi

Institutions: National Hospital for Neurology and Neurosurgery, UCL Queen Square Institute of Neurology, University College London, West Virginia University, Harvard University, MRC Prion Unit, Technion – Israel Institute of Technology

Language: English

Topic: Prion Diseases and Protein Misfolding

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institute for Health and Care Research, Brain Research Trust, National Institutes of Health, Medical Research Council, National Institute of General Medical Sciences

Awards: G2482858607, Molecular Chaperones and Protein Degradation, G6399358109

OpenAlex ID: W1978810558

FWCI: 2.859

Cites: 60

Cited by: 122

Related to: 10