Work

Exacerbation of Nickel Induced Oxidative Response by Vitamin E.

Year: 1995

Type: article

Abstract: Vitamin E (alpha-tocopherol), a well known naturally occurring chain breaking antioxidant and a free radical scavenger was found to exacerbate nickel (Ni) toxicity in mice. Vitamin E (Vit. E) mediated enhancement of nickel toxicity was demonstrated by (i) enhanced mortality in mice treated with Ni and Vit. E (ii) increased hepatic lipid peroxidation, (iii) increased rate of benzoate hydroxylation, and (iv) liposomal membrane damage.

Source: Industrial Health

DOI: 10.2486/indhealth.33.143

Authors: Mirza M. HUSAIN, Nihal AHMAD, Sanjay GUPTA, Jai R. BEHARI, Syed K. HASAN, Sanjay K. SRIVASTAVA, Ramesh C. SRIVASTAVA

Institutions: Indian Institute of Toxicology Research, Case Western Reserve University

Language: English

Topic: Heavy Metal Exposure and Toxicity

Subfield: Health, Toxicology and Mutagenesis

Field: Environmental Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W1978890939

FWCI: 0.391

Cites: 34

Cited by: 4

Related to: 10