Year: 2009
Type: article
Abstract: Biomaterials synthesis and scaffold fabrication will play an increasingly important role in the design of systems for regenerative medicine and tissue engineering. These rapidly growing fields are converging as scaffold design must begin to incorporate multidisciplinary aspects in order to effectively organize cell-seeded constructs into functional tissue. This review article examines the use of synthetic biomaterials and fabrication strategies across length scales with the ultimate goal of guiding cell function and directing tissue formation. This discussion is parsed into three subsections: (1) biomaterials synthesis, including elastomers and gels; (2) synthetic micro- and nanostructures for engineering the cell–biomaterial interface; and (3) complex biomaterials systems design for controlling aspects of the cellular microenvironment.
Source: Pure and Applied Chemistry
Author: Christopher J. Bettinger
Institution: Stanford University
Language: English
Subfield: Molecular Medicine
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W1978969535