Work

Cord Blood Storage for ≥ 5 Years Does Not Impact Engraftment

Year: 2013

Type: article

Abstract: The impact of the years of storage of an umbilical cord blood unit (CBU) on its engraftment potency is not known. We analyzed engraftment kinetics of 15 Old CBUs defined as stored for more than 5 years and compared it to 71 Younger CBUs for end points of time to neutrophil and platelet engraftment. The median duration of storage for the Old CBUs was 5.6 years (5.6-12.2 years). For Old vs. Young CBUs, the average total nucleated count was 0.5 x106 vs. 55x106 (P = .004), cryopreservation volume of 72ml vs.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2012.11.470

Authors: Simrit Parmar, Marcos de Lima, Elizabeth J. Shpall, Gabriela Rondon

Institution: The University of Texas MD Anderson Cancer Center

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650