Year: 1985
Type: article
Abstract: Rat livers were perfused with 0.5% Triton X-100 for 30 to 60 min and studied by scanning electron microscope. Three-dimensional filamentous networks were visualized in the cytoplasm of hepatocytes in situ. Branching and end-to-side contacts of intermediate filaments, and intermediate filaments which were connected with microtubules and microfilaments were noted. Numerous filaments were observed in the perinuclear region and at the cell border. Filaments were attached to polyribosomes and nuclei. No differences were observed in the cytoplasmic cytoskeleton after treatment of the sample at 4 degrees C. These results support the concept that intermediate filaments mechanically integrate the cytoplasmic space.
Source: Hepatology
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W1980160702