Work

Self-assembly of peptides to nanostructures

Year: 2014

Type: review

Abstract: The formation of well-ordered nanostructures through self-assembly of diverse organic and inorganic building blocks has drawn much attention owing to their potential applications in biology and chemistry. Among all organic building blocks, peptides are one of the most promising platforms due to their biocompatibility, chemical diversity, and resemblance to proteins. Inspired by the protein assembly in biological systems, various self-assembled peptide structures have been constructed using several amino acids and sequences. This review focuses on this emerging area, the recent advances in peptide self-assembly, and formation of different nanostructures, such as tubular structures, fibers, vesicles, and spherical and rod-coil structures. While different peptide nanostructures have been discovered, potential applications are explored in drug delivery, tissue engineering, wound healing, and surfactants.

Source: Organic & Biomolecular Chemistry

DOI: 10.1039/c4ob00447g

Authors: Dindyal Mandal, Amir Nasrolahi Shirazi, Keykavous Parang

Institutions: KIIT University, Chapman University

Language: English

Topic: Supramolecular Self-Assembly in Materials

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

Funders: National Institute of General Medical Sciences, National Center for Research Resources

Awards: RI Network for Excellence in Biomedical and Behavioral Research, Rhode Island IDeA Network of Biomedical Research Excellence