Work

KIR B or not to be?...that is the question for ALL

Year: 2014

Type: article

Abstract: In this issue of Blood, Oevermann et al report on a cohort of 85 children (median age, 10 years) undergoing T-cell–depleted haploidentical hematopoietic cell transplantation (HCT) for acute lymphoblastic leukemia (ALL), where variations in the killer-cell immunoglobulin-like receptor (KIR) gene “content” of the donor were associated with significantly less relapse and improved disease-free survival.(1)

Source: Blood

DOI: 10.1182/blood-2014-09-596395

Authors: Michael R. Verneris, Jeffrey S. Miller

Institution: University of Minnesota

Language: English

Topic: Immune Cell Function and Interaction

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, National Institute of Allergy and Infectious Diseases