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mTOR-Raptor Binds and Activates SGK1 to Regulate p27 Phosphorylation

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Year: 2008
Type: article
Source: Molecular Cell
DOI: 10.1016/j.molcel.2008.04.027
Authors: Feng Hong, Michelle D. Larrea, Cheryl Doughty, David J. Kwiatkowski, Rachel Squillace, Joyce M. Slingerland
Institutions: University of Miami, Sylvester Comprehensive Cancer Center, Brigham and Women's Hospital, Harvard University, ARIAD Pharmaceuticals (United States)
Language: English

Topic: PI3K/AKT/mTOR signaling in cancer
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Cancer Institute
Awards: Effects of the PI3K Pathway on p27 Function and Cancer Progression, The involvement of p90-RSK in the deregulation of p27, Molecular Pathogenesis of the Hamartoma Syndromes
OpenAlex ID: W1980848382
FWCI: 10.07
Cites: 73
Cited by: 261
Related to: 9
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