Work

Stimulation of DNA and Protein Synthesis in Fetal-Rat Liver Cells by Serum from Partially Hepatectomized Rats

Year: 1972

Type: article

Abstract: Primary cultures of differentiated liver cells from fetal rats respond to serum from partially hepatectomized rats by an increased uptake of [(3)H]thymidine and [(3)H]leucine as compared with cultures incubated with normal rat serum. These findings are discussed in relation to the mechanism of induction of DNA synthesis and growth in liver cells during liver regeneration.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.69.2.374

Authors: Dieter Paul, Hyam Leffert, Gordon Sato, Robert W. Holley

Institutions: Salk Institute for Biological Studies, Albert Einstein College of Medicine, University of California San Diego

Language: English

Topic: Liver physiology and pathology

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1981764336

FWCI: 9.47

Cites: 27

Cited by: 45

Related to: 10