Work

Selection and evaluation of clinically relevant AAV variants in a xenograft liver model

Year: 2013

Type: article

Source: Nature

DOI: 10.1038/nature12875

Authors: Leszek Lisowski, Allison P. Dane, Kirk Chu, Yue Zhang, Sharon C. Cunningham, Elizabeth M. Wilson, Sean Nygaard, Markus Grompe, Ian E. Alexander, Mark A. Kay

Institutions: Salk Institute for Biological Studies, Stanford Medicine, University College London, Stanford University, Children's Medical Research Institute, Children's Hospital at Westmead, Yecuris (United States), Oregon Health & Science University, The University of Sydney

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Heart, Lung, and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: Transgene Persistence in Liver Gene Therapy, G3104719123, G3392916807, Molecular Evolution Strategies to Derive New Recombinant AAV Vectors, G5560938479, Hepatic gene transfer for the treatment of hemophilia B and other genetic diseases

OpenAlex ID: W1981950767

FWCI: 21.15

Cites: 36

Cited by: 451

Related to: 10