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Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

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Year: 1991
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/jm00105a017
Authors: William D. Kingsbury, Jeffrey C. Boehm, Dalia R. Jakas, Kenneth G. Holden, Sidney M. Hecht, Gregory Gallagher, Mary Jo Caranfa, Francis L. McCabe, Leo F. Faucette, Randall K. Johnson, Robert P. Hertzberg
Institutions: GlaxoSmithKline (United Kingdom), University of Virginia
Language: English

Topic: Cancer therapeutics and mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: National Cancer Institute
Award: TOPOISOMERASES AS NEW THERAPEUTIC TARGETS
OpenAlex ID: W1981987977
FWCI: 5.006
Cites:
Cited by: 525
Related to: 10
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