Work

Hospital-Acquired Infections Due to Gram-Negative Bacteria

Year: 2010

Type: review

Abstract: Hospital-acquired infections are most commonly associated with mechanical ventilation, invasive medical devices, or surgical procedures. Gram-negative bacteria are responsible for more than 30% of hospital-acquired infections and predominate in hospital-acquired pneumonia. They are highly efficient at up-regulating or acquiring mechanisms of antibiotic drug resistance, especially in the presence of antibiotic selection pressure. This review updates what clinicians should know about these often life-threatening infections.

Source: New England Journal of Medicine

DOI: 10.1056/nejmra0904124

Authors: Anton Y. Peleg, David C. Hooper

Institutions: Beth Israel Deaconess Medical Center, Harvard University, Massachusetts General Hospital, Monash University

Language: English

Topic: Nosocomial Infections in ICU

Subfield: Critical Care and Intensive Care Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases