Work

Discovery of Tofogliflozin, a Novel C-Arylglucoside with an O-Spiroketal Ring System, as a Highly Selective Sodium Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

Year: 2012

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/jm300884k

Authors: Yoshihito Ohtake, Tsutomu Sato, Takamitsu Kobayashi, Masahiro Nishimoto, Naoki Taka, Koji Takano, Keisuke Yamamoto, Masayuki Ohmori, Marina Yamaguchi, Kyoko Takami, Sang-Yong Yeu, Koo-Hyeon Ahn, Hiroharu Matsuoka, Kazumi Morikawa, Masayuki Suzuki, Hitoshi Hagita, Kazuharu Ozawa, Koji Yamaguchi, Motohiro Kato, Sachiya Ikeda

Institutions: Chugai Pharmaceutical Co., Ltd. (Japan), Chugai Research Institute For Medical Science, Inc. (Japan), Sungkyunkwan University

Language: English

Topic: Diabetes Treatment and Management

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Bristol-Myers Squibb, Soochow University, Chugai Pharmaceutical

OpenAlex ID: W1982261994

FWCI: 10.09

Cites: 45

Cited by: 174

Related to: 10