Work

Serum Galactomannan and (1→3)-β- d -Glucan Assays for Patients with Multiple Myeloma and Waldenstrom's Macroglobulinemia

Year: 2011

Type: article

Abstract: We assessed the performance of galactomannan and (1→3)-β-d-glucan in 29 serum samples from patients with multiple myeloma and Waldenstrom's macroglobulinemia without invasive fungal disease to address issues of false positivity and uninterpretable results previously reported among patients with these conditions. Galactomannan and (1→3)-β-d-glucan assays were not falsely elevated in any patient. (1→3)-β-d-glucan assay results were uninterpretable in 24% of patients. Patients with IgG levels of >2,000 mg/dl had higher odds of uninterpretable (1→3)-β-d-glucan results.

Source: Journal of Clinical Microbiology

DOI: 10.1128/jcm.06295-11

Authors: Nicolas C. Issa, Sophia Koo, Robert C. Lynch, Charline Gay, Sarah P. Hammond, Lindsey R. Baden, Irene M. Ghobrial, Malcolm A. Finkelman, Francisco M. Marty

Institutions: Brigham and Women's Hospital, Harvard University, Dana-Farber Cancer Institute

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1982917209

FWCI: 0.4

Cites: 20

Cited by: 7

Related to: 10