Work

Changing the peptide specificity of a human T-cell receptor by directed evolution

Year: 2014

Type: article

Source: Nature Communications

DOI: 10.1038/ncomms6223

Authors: Sheena N. Smith, Yuhang Wang, Javier L. Baylon, Nishant K. Singh, Brian M. Baker, Emad Tajkhorshid, David M. Kranz

Institutions: University of Illinois Urbana-Champaign, University of Illinois System, University of Notre Dame, Mike and Josie Harper Cancer Research Institute

Language: English

Topic: T-cell and B-cell Immunology

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Melanoma Research Alliance, National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences

Awards: Center for Macromolecular Modeling and Bioinformatics, Development of a Computational Framework for TCR Engineering, G4994162000, Engineering T Cell Receptors for Adoptive Cell Therapies, G6091918606, Training Program at the Chemistry-Biology Interface, G7038426841, Physical Basis for T Cell Receptor Binding and Activity, Membrane Protein Structural Dynamics Consortium, G9000013378, G9000161401

OpenAlex ID: W1983063722

FWCI: 0.913

Cites: 69

Cited by: 29

Related to: 10