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The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activation

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Year: 2013
Type: article
Source: Toxicology and Applied Pharmacology
DOI: 10.1016/j.taap.2013.09.010
Authors: Kuo Du, C. David Williams, Mitchell R. McGill, Yuchao Xie, Anwar Farhood, Mathieu Vinken, Hartmut Jaeschke
Institutions: University of Kansas Medical Center, St David's Medical Center, Vrije Universiteit Brussel
Language: English

Topic: Drug-Induced Hepatotoxicity and Protection
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Environmental Health Sciences, National Center for Research Resources
Awards: G11419619, G1377672508, G2115522101, G2704092023, Mechanisms of Neutrophil-induced Liver Toxicity, G3126934232, G3900448260, G602775177, Training Program in Environmental Toxicology, Mitochondrial Dysfunction and Drug Hepatotoxicity, G9000229363
OpenAlex ID: W1983079940
FWCI: 5.814
Cites: 51
Cited by: 49
Related to: 10
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