Work

Photodynamic therapy of hypervascular cutaneous tissues in animal models using porphyrin or phthalocyanine activated by red light

Year: 1990

Type: conference-paper

Abstract: Continued iraprovement in the results of laser treatment of portwine stain (PWS) , with reduction in scarring, will depend on the ability to use lasers to induce selective injury of only the abnormal blood vessels in the dennis . Photodynamic therapy (PDT), using an exogenous photosensitizing drug specifically activated by a certain wavelength of light, may be used to destroy selectively certain targets in biological systems. The current study demonstrates, in the chicken comb animal model, that PDT using porphyrins and phthalocyanines activated by red light could be used to treat hypervascular derinal tissues.

Source: Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE

DOI: 10.1117/12.17453

Authors: J. Stuart Nelson, Arie Orenstein, Lih-Huei L. Liaw, Sol Kimel, Michael W. Berns

Institutions: University of California, Irvine, Beckman Laser Institute and Medical Clinic

Language: English

Topic: Photodynamic Therapy Research Studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Defense, National Institutes of Health