Year: 2003
Type: article
Study design: Observational Study
Abstract: The molecular identification of Mycobacterium tuberculosis DNA in ancient human remains has been achieved mainly in mummies with macroscopic changes but not in the skeletons without bone tuberculosis. Using polymerase chain reaction studies, we identified mycobacterial DNA in 2000-year-old human skeletons without pathological changes. Our findings suggest that these people suffered from an outbreak of tuberculosis. Molecular examinations for mycobacterial DNA in the bone marrow of skeletons may contribute to the clarification of ancient diseases in old human populations.
Source: Kansenshogaku zasshi
Authors: Hisae FUSEGAWA, BING-HUA Wang, Kiyohiko SAKURAI, Kazutoshi NAGASAWA, Mitsuzane OKAUCHI, Kouichi NAGAKURA
Institutions: Tokai University, Waseda University, Tunghai University
Language: English
Subfield: Archeology
Field: Arts and Humanities
Domain: Social Sciences
Open Access status: bronze
OpenAlex ID: W1983447375