Advanced Material Strategies for Tissue Engineering Scaffolds
Year: 2009
Type: article
Abstract: Tissue engineering seeks to restore the function of diseased or damaged tissues through the use of cells and biomaterial scaffolds. It is now apparent that the next generation of functional tissue replacements will require advanced material strategies to achieve many of the important requirements for long‐term success. Here, we provide representative examples of engineered skeletal and myocardial tissue constructs in which scaffolds were explicitly designed to match native tissue mechanical properties as well as to promote cell alignment. We discuss recent progress in microfluidic devices that can potentially serve as tissue engineering scaffolds, since mass transport via microvascular‐like structures will be essential in the development of tissue engineered constructs on the length scale of native tissues. Given the rapid evolution of the field of tissue engineering, it is important to consider the use of advanced materials in light of the emerging role of genetics, growth factors, bioreactors, and other technologies.
Source: Advanced Materials
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: Hip Joint Resurfacing with Functional Human Cartilage, Cell Adhesion and Guidance Motifs for Cardiac Grafts, Biomechanics and Inflammation in Osteoarthritis, Hip-Joint Resurfacing with Functional Human Cartilage, Intrinsic Repair of the Knee Meniscus, Viscoelastic Properties of Normal and OA Chondrons, Hip-Joint Resurfacing with Functional Human Cartilage
OpenAlex ID: W1983704013