Year: 1963
Type: article
Abstract: This study describes the development of a method for the recognitionand definition of leucocyte group Four. The method can also be
applied to the detection of other leucocyte groups. Essential factors
in the method were:
a) the use of leucocyte agglutinins formed during pregnancy;
b) an insight into the shortcomings of the agglutination test;
c) the use of statistical methods to overcome these shortcomings; and
d) the use of a panel consisting of the leucocytes of the women who
had formed the agglutinins, and of those of their husbands.
This study describes the development of a method for the recognition
and definition of leucocyte group Four. The method can also be
applied to the detection of other leucocyte groups. Essential factors
in the method were:
a) the use of leucocyte agglutinins formed during pregnancy;
b) an insight into the shortcomings of the agglutination test;
c) the use of statistical methods to overcome these shortcomings; and
d) the use of a panel consisting of the leucocytes of the women who
had formed the agglutinins, and of those of their husbands.
DOI: 10.1172/jci104822
Authors: J. J. Van Rood, A. Van Leeuwen
Language: English
Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W1983896644