Work

Protein acetylation: more than chromatin modification to regulate transcription

Year: 1997

Type: article

Abstract: Histone acetyltransferases and deacetylases are involved in the regulation of gene transcription. Recently, tumor suppressor protein p53 has been shown to be a target for transcriptional coactivators that have histone acetyltransferase activity, suggesting acetylation is also involved in the regulation of cell proliferation and tumorigenesis.

Source: Chemistry & Biology

DOI: 10.1016/s1074-5521(97)90296-9

Authors: J.Henri Bayle, Gerald R. Crabtree

Institutions: Howard Hughes Medical Institute, Stanford Medicine, Stanford University

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

OpenAlex ID: W1984618677

FWCI: 0.356

Cites: 26

Cited by: 33

Related to: 10