Work

Paneth cells and necrotizing enterocolitis

Year: 2012

Type: article

Abstract: Necrotizing enterocolitis (NEC) is a common and devastating disease of premature infants. Immaturity of the innate immune system of the gut is central to the pathogenesis of NEC. Recent studies suggest a key role for Paneth cells in this disease. Addressing basic questions on the development and function of immature Paneth cells may shed light on the puzzling pathophysiology of NEC. Current animal models of NEC are limited in their capacity to answer these questions.

Source: Gut Microbes

DOI: 10.4161/gmic.21738

Author: Mark A. Underwood

Institutions: University of California Davis Medical Center, University of California, Davis

Language: English

Topic: Infant Nutrition and Health

Subfield: Nutrition and Dietetics

Field: Nursing

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,060