Work

A protocol for the measurement of myocardial blood volume and water exchange

Year: 2011

Type: article

Abstract: Absolute myocardial perfusion MR imaging (ml/min/100g tissue) has the potential to timely diagnose and reduce patient mortality from coronary artery disease. Organ perfusion can be quantified by direct calibration of relative perfusion images using absolute blood volume (ml/100g) [ 1 ]. It is well known that for an intravascular gadolinium-based T1 shortening contrast agent, the parenchymal T1 change reflects tissue blood volume [ 2 ].However, to accurately quantify blood flow from blood volume, we must describe the compartmentalization effects of intra- to extra-vascular water exchange [ 2 , 3 ].

Source: Journal of Cardiovascular Magnetic Resonance

DOI: 10.1186/1532-429x-13-s1-p140

Authors: Octavia Biris, Neil Chatterjee, James Carr

Institution: Northwestern University

Language: English

Topic: Cardiac Imaging and Diagnostics

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,000