Work

Berberine: A Potential Multipotent Natural Product to Combat Alzheimer’s Disease

Year: 2011

Type: article

Abstract: With the accelerated aging of human society Alzheimer's disease (AD) has become one of the most threatening diseases in the elderly. However, there is no efficient therapeutic agent to combat AD. Berberine is a natural isoquinoline alkaloid that possesses a wide range of pharmacological effects. In the present paper, we review the multiple activities of berberine, including antioxidant, acetylcholinesterase and butyrylcholinesterase inhibitory, monoamine oxidase inhibitory, amyloid-b peptide level-reducing and cholesterol-lowering activities, which suggest that berberine may act as a promising multipotent agent to combat AD.

Source: Molecules

DOI: 10.3390/molecules16086732

Authors: Hong-Fang Ji, Liang Shen

Institution: Shandong University of Technology

Language: English

Topic: Berberine and alkaloids research

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,258