Work

Dysfunctional telomeres activate an ATM‐ATR‐dependent DNA damage response to suppress tumorigenesis

Year: 2007

Type: article

Source: The EMBO Journal

DOI: 10.1038/sj.emboj.7601893

Authors: Xiaolan Guo, Yibin Deng, Yahong Lin, Wilfredo Cosme‐Blanco, Suzanne Chan, Hua He, Guohua Yuan, Eric J Brown, Sandy Chang

Institutions: North Sichuan Medical University, The University of Texas MD Anderson Cancer Center, University of Pennsylvania

Language: English

Topic: Telomeres, Telomerase, and Senescence

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Welch Foundation, Elsa U. Pardee Foundation, Sidney Kimmel Foundation for Cancer Research, Sidney Kimmel Foundation, Abraham J. and Phyllis Katz Foundation, National Institute on Aging, National Cancer Institute

Awards: Telomere dysfunction, p53 and tumorigenesis, The role of the telomere capping protein POT1 in mammalian aging, Replicative Senescence as a Tumor Suppressive Mechanism

OpenAlex ID: W1985964699

FWCI: 6.117

Cites: 56

Cited by: 253

Related to: 10